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DermExcel™

Rejuvenize Peel

4.9 / 5.0 from 464 reviews

anti-aging

↓ pigmentation

Exfoliating

renew skin cells

Brightening

Superficial peel with anti-inflammatory, antioxidant and keratolytic action.

Provides fibroblast-stimulating and antioxidant action with a pH of 1.5. It works by thinning the stratum corneum, promoting epidermolysis, dispersing melanin in the basal layer, and boosting both epidermal and dermal hyaluronic acid and collagen gene expression. This is achieved through an elevated secretion of Interleukin 6 (IL-6), resulting in enhanced skin clarity and resilience.

Designed to elevate your skincare journey to new heights. Expertly formulated with potent concentrations of Glycolic acid – 25%; 35% and 50%.

25% Glycolic acid

Glycolic acid is highly acclaimed for its remarkable exfoliating and rejuvenating properties. Its small molecular size enables deep skin penetration, fostering efficient exfoliation at the cellular level.

Glycolic acid’s water solubility allows it to penetrate the upper layers of the skin easily. Its primary mechanism of action involves weakening the bonds between dead skin cells, promoting their shedding, and revealing the newer, healthier skin beneath. This process of accelerated cell turnover is instrumental in addressing a range of skin concerns, from aging signs like fine lines and wrinkles to texture irregularities and hyperpigmentation.

Glycolic acid's efficacy extends beyond mere exfoliation. It's also recognized for stimulating collagen production, a crucial protein in maintaining skin's elasticity and firmness. This aspect contributes to its anti-aging benefits. Furthermore, its hydrating properties add to its appeal, as they help increase the skin's capacity to retain moisture, leading to a more supple and vibrant complexion.

Clinical studies have consistently supported glycolic acid's role in improving skin appearance. Research indicates significant improvements in skin texture and pigmentation and the visible reduction of wrinkles and fine lines with glycolic acid.

Physiological Effects

Exfoliation: Glycolic acid is a powerful exfoliant. It dissolves the bonds between dead skin cells on the skin’s surface, facilitating their removal and revealing newer, healthier skin underneath.
Increased Collagen Production: It stimulates collagen production, which is essential for skin elasticity and firmness. This action helps reduce the appearance of fine lines and wrinkles.
Enhanced Skin Hydration: Glycolic acid improves the skin's ability to retain moisture, enhancing hydration and a more plump, vibrant skin appearance.
Skin Brightening: Removing dead skin cells can brighten the complexion and reduce the appearance of dark spots and hyperpigmentation.
Improved Skin Texture: Regular use of glycolic acid can lead to smoother, more even textured skin, making it beneficial for conditions like keratosis pilaris.
Acne Treatment: Its exfoliating properties help in unclogging pores, thereby reducing the occurrence of acne breakouts.

Role in Managing Dermatological Conditions

Aging Skin: Glycolic acid is widely used in anti-aging products to reduce signs of aging, such as fine lines, wrinkles, and age spots.
Acne-Prone Skin: It helps manage acne by exfoliating the skin and removing blockage from pores.
Hyperpigmentation: It effectively treats hyperpigmentation by accelerating the removal of hyperpigmented skin cells.
Textural Irregularities: Glycolic acid can improve skin texture and is beneficial for treating keratosis pilaris and other conditions of rough skin.
Sun-Damaged Skin: It helps rejuvenate sun-damaged skin by accelerating cell turnover and collagen synthesis.

References

Bernstein, E. F. (2001). Glycolic acid treatment increases type I collagen mRNA and hyaluronic acid content of human skin. Dermatologic Surgery.
Kornhauser, A., Coelho, S. G., & Hearing, V. J. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, Cosmetic and Investigational Dermatology.
Sharad, J. (2013). Glycolic acid peel therapy – a current review. Clinical, Cosmetic and Investigational Dermatology.
Smith, W. P. (1996). Epidermal and dermal effects of topical lactic acid. Journal of the American Academy of Dermatology, 35(3), 388-391.

35% Glycolic acid

Physiological Effects

Exfoliation: Glycolic acid is a powerful exfoliant. It dissolves the bonds between dead skin cells on the skin’s surface, facilitating their removal and revealing newer, healthier skin underneath.
Increased Collagen Production: It stimulates collagen production, which is essential for skin elasticity and firmness. This action helps reduce the appearance of fine lines and wrinkles.
Enhanced Skin Hydration: Glycolic acid improves the skin's ability to retain moisture, enhancing hydration and a more plump, vibrant skin appearance.
Skin Brightening: Removing dead skin cells can brighten the complexion and reduce the appearance of dark spots and hyperpigmentation.
Improved Skin Texture: Regular use of glycolic acid can lead to smoother, more even textured skin, making it beneficial for conditions like keratosis pilaris.
Acne Treatment: Its exfoliating properties help in unclogging pores, thereby reducing the occurrence of acne breakouts.

Role in Managing Dermatological Conditions

Aging Skin: Glycolic acid is widely used in anti-aging products to reduce signs of aging, such as fine lines, wrinkles, and age spots.
Acne-Prone Skin: It helps manage acne by exfoliating the skin and removing blockage from pores.
Hyperpigmentation: It effectively treats hyperpigmentation by accelerating the removal of hyperpigmented skin cells.
Textural Irregularities: Glycolic acid can improve skin texture and is beneficial for treating keratosis pilaris and other conditions of rough skin.
Sun-Damaged Skin: It helps rejuvenate sun-damaged skin by accelerating cell turnover and collagen synthesis.

References

Bernstein, E. F. (2001). Glycolic acid treatment increases type I collagen mRNA and hyaluronic acid content of human skin. Dermatologic Surgery.
Kornhauser, A., Coelho, S. G., & Hearing, V. J. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, Cosmetic and Investigational Dermatology.
Sharad, J. (2013). Glycolic acid peel therapy – a current review. Clinical, Cosmetic and Investigational Dermatology.
Smith, W. P. (1996). Epidermal and dermal effects of topical lactic acid. Journal of the American Academy of Dermatology, 35(3), 388-391.

50% Glycolic acid

Physiological Effects

Exfoliation: Glycolic acid is a powerful exfoliant. It dissolves the bonds between dead skin cells on the skin’s surface, facilitating their removal and revealing newer, healthier skin underneath.
Increased Collagen Production: It stimulates collagen production, which is essential for skin elasticity and firmness. This action helps reduce the appearance of fine lines and wrinkles.
Enhanced Skin Hydration: Glycolic acid improves the skin's ability to retain moisture, enhancing hydration and a more plump, vibrant skin appearance.
Skin Brightening: Removing dead skin cells can brighten the complexion and reduce the appearance of dark spots and hyperpigmentation.
Improved Skin Texture: Regular use of glycolic acid can lead to smoother, more even textured skin, making it beneficial for conditions like keratosis pilaris.
Acne Treatment: Its exfoliating properties help in unclogging pores, thereby reducing the occurrence of acne breakouts.

Role in Managing Dermatological Conditions

Aging Skin: Glycolic acid is widely used in anti-aging products to reduce signs of aging, such as fine lines, wrinkles, and age spots.
Acne-Prone Skin: It helps manage acne by exfoliating the skin and removing blockage from pores.
Hyperpigmentation: It effectively treats hyperpigmentation by accelerating the removal of hyperpigmented skin cells.
Textural Irregularities: Glycolic acid can improve skin texture and is beneficial for treating keratosis pilaris and other conditions of rough skin.
Sun-Damaged Skin: It helps rejuvenate sun-damaged skin by accelerating cell turnover and collagen synthesis.

References

Bernstein, E. F. (2001). Glycolic acid treatment increases type I collagen mRNA and hyaluronic acid content of human skin. Dermatologic Surgery.
Kornhauser, A., Coelho, S. G., & Hearing, V. J. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, Cosmetic and Investigational Dermatology.
Sharad, J. (2013). Glycolic acid peel therapy – a current review. Clinical, Cosmetic and Investigational Dermatology.
Smith, W. P. (1996). Epidermal and dermal effects of topical lactic acid. Journal of the American Academy of Dermatology, 35(3), 388-391.

USE DURING PREGNANCY

Rejuvenize Peel is safe to use during pregnancy.

SHIPPING

Shipping Guarantee: Guiding you to healthy skin isn’t only about our products; it's also about getting them to you as swiftly as the science behind them. That's why Dermal Health offers a shipping guarantee you can rely on.
Where We Ship From: Orders are dispatched from our facilities in Pretoria.
Who We Ship With: We trust only well-known, popular, and dependable courier services with your packages.
When You'll Get It: Expect confident skin soon! Shipping addresses in Pretoria and Johannesburg will enjoy delivery from same-day to 2 business days. Shipping addresses further from Pretoria may expect delivery within 1-4 business days, depending on the service you select during checkout. Your estimated delivery date will reflect during checkout so that you can mark your calendar.
Tracking Your Order: Eager to start your DermExcel journey? We don't blame you! You'll receive a tracking number after you place your order so that you can follow your package.

For any shipping inquiries, our customer service team is ready to assist.

RETURNS

Dermal Health Science 30-Day Confidence Guarantee: We are passionate about guiding you to healthy skin through medical science. We believe in the quality and effectiveness of our products so much that we offer a 30-Day Confidence Guarantee. If you're unsatisfied with your purchase, simply return it within 30 days for a full refund.

Healthy Skin Is Not Complicated and neither is our return policy. Please visit our detailed return policy or contact our friendly customer service team for more information.

Feel as confident in us as we want you to feel in your skin.

SECURE PAYMENT

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Our Secure Payment Promise backs every transaction with DermExcel. We partner with trusted payment providers to create the best shopping experience for you.

Simple. Effective. Ethical. That's not just our skincare philosophy but our approach to your security too.

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Aging Related Conditions: Stimulates collagen production to reduce the appearance of fine lines and improve skin elasticity.
Actinic Keratosis: Promotes the shedding of the outer skin layers, smoothing the texture and reducing visible roughness associated with AK.
Photodamage: Reduces signs of sun damage, such as pigmentation and roughness.
Hyperpigmentation: Fades dark spots, melasma, and post-inflammatory pigmentation for a more even skin tone.
Acne and Congested Pores: Helps to unclog pores and prevent breakouts, especially in non-inflammatory acne.
Dull and Lifeless Skin: Promotes cell turnover for a brighter, more radiant complexion.
Keratosis Pilaris: The exfoliating action reduces the small, rough bumps caused by this condition.
Sun Damage: Repairs UV-induced skin damage by improving tone, texture, and reducing sunspots.

Active ingredients

25% Glycolic acid

Exfoliation: Glycolic acid is a powerful exfoliant. It dissolves the bonds between dead skin cells on the skin’s surface, facilitating their removal and revealing newer, healthier skin underneath.
Increased Collagen Production: It stimulates collagen production, which is essential for skin elasticity and firmness. This action helps reduce the appearance of fine lines and wrinkles.
Enhanced Skin Hydration: Glycolic acid improves the skin's ability to retain moisture, enhancing hydration and a more plump, vibrant skin appearance.
Skin Brightening: Removing dead skin cells can brighten the complexion and reduce the appearance of dark spots and hyperpigmentation.
Improved Skin Texture: Regular use of glycolic acid can lead to smoother, more even textured skin, making it beneficial for conditions like keratosis pilaris.
Acne Treatment: Its exfoliating properties help in unclogging pores, thereby reducing the occurrence of acne breakouts.

Aging Skin: Glycolic acid is widely used in anti-aging products to reduce signs of aging, such as fine lines, wrinkles, and age spots.
Acne-Prone Skin: It helps manage acne by exfoliating the skin and removing blockage from pores.
Hyperpigmentation: It effectively treats hyperpigmentation by accelerating the removal of hyperpigmented skin cells.
Textural Irregularities: Glycolic acid can improve skin texture and is beneficial for treating keratosis pilaris and other conditions of rough skin.
Sun-Damaged Skin: It helps rejuvenate sun-damaged skin by accelerating cell turnover and collagen synthesis.

Bernstein, E. F. (2001). Glycolic acid treatment increases type I collagen mRNA and hyaluronic acid content of human skin. Dermatologic Surgery.
Kornhauser, A., Coelho, S. G., & Hearing, V. J. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, Cosmetic and Investigational Dermatology.
Sharad, J. (2013). Glycolic acid peel therapy – a current review. Clinical, Cosmetic and Investigational Dermatology.
Smith, W. P. (1996). Epidermal and dermal effects of topical lactic acid. Journal of the American Academy of Dermatology, 35(3), 388-391.

35% Glycolic acid

Exfoliation: Glycolic acid is a powerful exfoliant. It dissolves the bonds between dead skin cells on the skin’s surface, facilitating their removal and revealing newer, healthier skin underneath.
Increased Collagen Production: It stimulates collagen production, which is essential for skin elasticity and firmness. This action helps reduce the appearance of fine lines and wrinkles.
Enhanced Skin Hydration: Glycolic acid improves the skin's ability to retain moisture, enhancing hydration and a more plump, vibrant skin appearance.
Skin Brightening: Removing dead skin cells can brighten the complexion and reduce the appearance of dark spots and hyperpigmentation.
Improved Skin Texture: Regular use of glycolic acid can lead to smoother, more even textured skin, making it beneficial for conditions like keratosis pilaris.
Acne Treatment: Its exfoliating properties help in unclogging pores, thereby reducing the occurrence of acne breakouts.

Aging Skin: Glycolic acid is widely used in anti-aging products to reduce signs of aging, such as fine lines, wrinkles, and age spots.
Acne-Prone Skin: It helps manage acne by exfoliating the skin and removing blockage from pores.
Hyperpigmentation: It effectively treats hyperpigmentation by accelerating the removal of hyperpigmented skin cells.
Textural Irregularities: Glycolic acid can improve skin texture and is beneficial for treating keratosis pilaris and other conditions of rough skin.
Sun-Damaged Skin: It helps rejuvenate sun-damaged skin by accelerating cell turnover and collagen synthesis.

Bernstein, E. F. (2001). Glycolic acid treatment increases type I collagen mRNA and hyaluronic acid content of human skin. Dermatologic Surgery.
Kornhauser, A., Coelho, S. G., & Hearing, V. J. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, Cosmetic and Investigational Dermatology.
Sharad, J. (2013). Glycolic acid peel therapy – a current review. Clinical, Cosmetic and Investigational Dermatology.
Smith, W. P. (1996). Epidermal and dermal effects of topical lactic acid. Journal of the American Academy of Dermatology, 35(3), 388-391.

50% Glycolic acid

Exfoliation: Glycolic acid is a powerful exfoliant. It dissolves the bonds between dead skin cells on the skin’s surface, facilitating their removal and revealing newer, healthier skin underneath.
Increased Collagen Production: It stimulates collagen production, which is essential for skin elasticity and firmness. This action helps reduce the appearance of fine lines and wrinkles.
Enhanced Skin Hydration: Glycolic acid improves the skin's ability to retain moisture, enhancing hydration and a more plump, vibrant skin appearance.
Skin Brightening: Removing dead skin cells can brighten the complexion and reduce the appearance of dark spots and hyperpigmentation.
Improved Skin Texture: Regular use of glycolic acid can lead to smoother, more even textured skin, making it beneficial for conditions like keratosis pilaris.
Acne Treatment: Its exfoliating properties help in unclogging pores, thereby reducing the occurrence of acne breakouts.

Aging Skin: Glycolic acid is widely used in anti-aging products to reduce signs of aging, such as fine lines, wrinkles, and age spots.
Acne-Prone Skin: It helps manage acne by exfoliating the skin and removing blockage from pores.
Hyperpigmentation: It effectively treats hyperpigmentation by accelerating the removal of hyperpigmented skin cells.
Textural Irregularities: Glycolic acid can improve skin texture and is beneficial for treating keratosis pilaris and other conditions of rough skin.
Sun-Damaged Skin: It helps rejuvenate sun-damaged skin by accelerating cell turnover and collagen synthesis.

Bernstein, E. F. (2001). Glycolic acid treatment increases type I collagen mRNA and hyaluronic acid content of human skin. Dermatologic Surgery.
Kornhauser, A., Coelho, S. G., & Hearing, V. J. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, Cosmetic and Investigational Dermatology.
Sharad, J. (2013). Glycolic acid peel therapy – a current review. Clinical, Cosmetic and Investigational Dermatology.
Smith, W. P. (1996). Epidermal and dermal effects of topical lactic acid. Journal of the American Academy of Dermatology, 35(3), 388-391.

Full ingredient list

Glycolic acid: 25% | 35% | 50%

1. Cleanse

Cleanse the skin with any DermExcel™ Cleanser.

2. Prep

Use the Pre-Peel Solution to remove excess oil from the skin.

3. Treat

Apply 1-2 ml of the peel solution using cotton buds or a brush. Leave the solution on the skin.
For 25% strength, leave on for 2-5 minutes based on skin condition and patient tolerance.
For 35% strength, leave on for 1-5 minutes based on skin condition and patient tolerance.
For 50% strength, leave on for 1-3 minutes based on skin condition and patient tolerance.
Neutralize with Post-peel Neutralizer.

4. Boost (optional)

For increased melanogenesis inhibition, collagen stimulation and hydration apply 1-2 pumps Collagen Serum - or Retinol Serum after neutralizing and gently spread over the treatment area.

5. Protect

Apply any DermExcel™ or Dermaplan™ Moisturizer followed by Dermdefense SPF50.

POST PEEL INSTRUCTIONS

Sun protection is critical. Avoid sun exposure and wear a broad-spectrum sunscreen with a minimum of SPF 30.
Do not pick or pull the skin. Allow skin to peel at its own pace. Premature peeling of the skin will result in dry, cracked, raw skin that may develop into post-inflammatory hyperpigmentation and scarring.
Avoid using chemical exfoliators, physical exfoliators, microdermabrasion, laser treatments, and waxing for 7 days after the peel procedure.
Do not re-apply make-up on the day of the peel procedure. Make-up can be applied from the following day.
Wash twice a day with a gentle cleanser and liberally apply DermNourish after cleansing and throughout the day as needed to prevent dryness and formation of crust.

* Resume all active ingredients after post-peel irritation subsided.

Anti-Aging

Glycolic acid penetrates deeply into the epidermis and stimulates fibroblast activity in the dermis, leading to increased production of collagen and elastin. This helps improve skin firmness and elasticity while reducing the appearance of fine lines and wrinkles.
The exfoliative effect of glycolic acid promotes cell turnover, removing damaged, older skin cells and revealing smoother, younger-looking skin.
Glycolic acid stimulates the production of collagen and elastin, smoothing the skin, reducing wrinkle depth, and enhancing elasticity by promoting the renewal of structural proteins within the dermis.

Actinic Damage Repair

Actinic keratosis presents as thickened, rough patches of skin due to abnormal keratinocyte buildup. Glycolic acid’s keratolytic properties break down the bonds between these abnormal cells, facilitating their removal.
By promoting epidermal turnover, glycolic acid helps replace damaged cells with healthier ones, reducing the thickness and appearance of these precancerous lesions.
Glycolic acid encourages the shedding of damaged keratinocytes, reducing lesion size and improving skin health while minimizing the buildup of abnormal cells that could develop into new lesions.

Photodamage Repair

Photodamaged skin often exhibits uneven texture, rough patches, and hyperpigmentation.
Glycolic acid exfoliates the surface layers of sun-damaged skin, improving texture and allowing fresh, healthy skin to emerge. By stimulating cell turnover, glycolic acid helps fade sun spots and smooth the skin, while promoting the repair of UV-damaged cells.
Glycolic acid eliminates rough, uneven patches caused by UV exposure while promoting the emergence of fresh, healthy skin cells, effectively diminishing visible signs of photodamage.

Pigmentation Treatment

Hyperpigmentation results from an accumulation of melanin in the epidermis. Glycolic acid exfoliates pigmented keratinocytes by breaking down the bonds between skin cells, allowing for the removal of dark spots and discoloration. By accelerating cell turnover, glycolic acid brings new, evenly pigmented skin to the surface, reducing the appearance of hyperpigmentation over time.
Glycolic acid removes pigmented skin cells to lighten areas of hyperpigmentation, promotes even skin tone through uniform exfoliation and cell renewal, and enhances overall brightness by revealing a clearer, more luminous complexion.

Exfoliation

The Rejuvenize Chemical Peel, with its high concentration of 25%, 35% and 50% Glycolic Acid, delivers powerful exfoliation that transforms the skin by promoting cell turnover, refining texture, and improving clarity.
It effectively addresses concerns such as aging, actinic keratosis, photodamage, hyperpigmentation, and dullness. By removing dead skin cells and stimulating collagen production, this peel leaves the skin smoother, brighter, and rejuvenated, revealing a healthier, more youthful appearance.

Skin Brightening & Rejuvenation

Dullness occurs when dead skin cells accumulate on the surface, blocking light reflection and giving the skin a tired, lackluster appearance.
Glycolic acid removes these dead cells, revealing the fresh, healthy skin underneath. This process enhances microcirculation and stimulates cell renewal, restoring the skin's natural glow.
Glycolic acid Clears dead skin buildup, allowing the skin to reflect light more evenly for a brighter appearance.