Medi-Zinc Cleanser

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DermExcel™

Medi-Zinc Cleanser

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5.0 / 5.0 from 862 reviews

Itch Relief

Anti-Acne

↓ inflammation

anti-redness

Anti-microbial

A powerful hypoallergenic medicated solution with beneficial properties attributed to its active constituent, Zinc Pyrithione. This chemical compound, FDA-approved and clinically recognized, delivers strong antibacterial and antifungal action, making the cleanser an ideal choice for managing skin conditions associated with redness, flaking, irritation, and itching.

Zinc Pyrithione's efficacy, compounded by a gentle cleansing base, facilitates the lifting and removing of impurities, leaving the complexion refreshed. Concurrently, it sustains a tranquil skin environment, reducing inflammation and discomfort. As a daily cleansing aid, Medi-Zinc Cleanser proposes a reliable, scientifically-backed intervention in fostering skin health and comfort.

SHIPPING

Shipping Guarantee: Guiding you to healthy skin isn’t only about our products; it's also about getting them to you as swiftly as the science behind them. That's why Dermal Health offers a shipping guarantee you can rely on.
Where We Ship From: Orders are dispatched from our facilities in Pretoria.
Who We Ship With: We trust only well-known, popular, and dependable courier services with your packages.
When You'll Get It: Expect confident skin soon! Shipping addresses in Pretoria and Johannesburg will enjoy delivery from same-day to 2 business days. Shipping addresses further from Pretoria may expect delivery within 1-4 business days, depending on the service you select during checkout. Your estimated delivery date will reflect during checkout so that you can mark your calendar.
Tracking Your Order: Eager to start your DermExcel journey? We don't blame you! You'll receive a tracking number after you place your order so that you can follow your package.

For any shipping inquiries, our customer service team is ready to assist.

RETURNS

Dermal Health Science 30-Day Confidence Guarantee: We are passionate about guiding you to healthy skin through medical science. We believe in the quality and effectiveness of our products so much that we offer a 30-Day Confidence Guarantee. If you're unsatisfied with your purchase, simply return it within 30 days for a full refund.

Healthy Skin Is Not Complicated and neither is our return policy. Please visit our detailed return policy or contact our friendly customer service team for more information.

Feel as confident in us as we want you to feel in your skin.

SECURE PAYMENT

Healthy Skin Is Not Complicated and neither is our return policy. Please visit our detailed return policy or contact our friendly customer service team for more information.

Feel as confident in us as we want you to feel in your skin.

Rosacea: The anti-inflammatory and antibacterial properties of Zinc Pyrithione help manage and alleviate the symptoms of rosacea.
Acne: The antibacterial properties of Zinc Pyrithione in Medi-Zinc Cleanser make it effective in managing acne by reducing bacteria on the skin's surface and controlling inflammation.
Seborrheic Dermatitis: This condition, which causes flaky, itchy, red skin, can be managed with the antifungal and anti-inflammatory properties of Zinc Pyrithione.
Redness: control and reduce redness associated with skin conditions like rosacea, dermatitis, and eczema.
Irritation: It is indicated for soothing skin irritation caused by various factors, including environmental aggressors, allergies, or sensitivities.
Itching: Medi-Zinc Cleanser provides relief from itching in itchy skin conditions such as contact dermatitis, insect bites, or allergic reactions.
Sensitive skin: Its hypoallergenic formulation makes it suitable for individuals with sensitive skin, providing a gentle and non-irritating cleansing option.
Psoriasis: The anti-inflammatory properties of Zinc Pyrithione can help manage the redness and irritation associated with psoriasis.
Eczema: While not a cure, the cleanser may help soothe the itching and inflammation associated with eczema.

Morning & Evening

Application time: Use in the morning and evening.
Frequency: Every day or as per your Dermal Diagnosis regimen instructions.

1. Wet fingers

Slightly wet your fingers for easier application. Do not wet your face before applying Medi-Zinc; this will cause the product to run into your eyes and sting.
Lather the areas you want to treat and make sure the product has good contact with the skin.

2. Treatment time

Keep the product in contact with your skin for at least 5 minutes, most preferably 10 minutes.
This will allow the product to penetrate the follicles optimally and ensure the active ingredient is effective.
Tip: Keep the cleanser on your skin while brushing your teeth, bathing, or getting dressed.

3. Rinse

Use a clean, wet, lukewarm face cloth or microfiber face sponge. This method provides better control, preventing the product from running into your eyes. Additionally, it effectively removes excess makeup and loose, peeling skin.

Important note

Repeat the application nightly for at least 3-4 weeks.
Because yeast, fungi, and bacteria do not develop resistance toward Zinc Pyrithione, you can continue to use Medi-Zinc cleanser regularly even after symptoms have cleared. Consistent application of Zinc Pyrithione will result in continuous antimicrobial activity.
Do not stop your treatment after all the signs and symptoms have cleared up. Problem areas should be in contact with Zinc Pyrithione at least once per week.
To keep the Malassezia yeast from returning, ensure enough Zinc Pyrithione is in contact with the skin around the problem areas.
Always remember the 5-10 minute skin contact rule.

Active ingredients

Zinc Pyrithione

Full Ingredient list

Aqua, Polyethylene Glycol, Coco-Glucoside, Cocoamidopropyl Betaine, Sodium Lauroyl Sarcosinate, Zinc Pyrithione, Phenoxyethanol & Ethyl hexyl Glycerin, Acrylates Copolymer, Triethanolamine, Coco-Glucoside & Glyceryl Oleate

Medi-Zinc Cleanser

product benefits

Antibacterial and Anti-fungal Action

Fights bacteria and fungi with 2% Zinc Pyrithione, reducing the risk of skin infections and helping to maintain a balanced and healthy skin microbiome.

Anti-inflammatory

Alleviates skin irritation and redness by targeting inflammatory pathways and markers, offering significant relief for inflamed skin conditions.

Reduce redness and irritation

Control and reduce skin discomfort symptoms such as redness, flaking, irritation, and itching, improving overall skin comfort.

Sebum Regulation

Implement effective sebum regulation strategies to minimize complications and refine the visual condition of oily skin.

Indications for Medi-Zinc Cleanser

Seborrheic Dermatitis
Facial and Body Acne
Rosacea / Red Skin
Inflammation
Clogged Pores
Folliculitis

Reduce redness

Sooth Irritated & Flaking Skin

Antibacterial and antifungal

Reduce inflammation

Healthy & comfortable skin

medi-zinc cleanser

mode of action

Anti-inflammatory

Inflammation on the skin contributes to itchiness, redness, and irritation, which are common symptoms of various skin conditions. Zinc Pyrithione reduces inflammation, which helps to alleviate these symptoms.
Zinc Pyrithione positively affects the immune system by balancing pro-inflammatory and anti-inflammatory cytokines in the body. Studies published in the Journal of Dermatological Science indicate that Zinc Pyrithione increases the production of anti-inflammatory cytokines in human skin cells. These cytokines are involved in the immune response, important for regulating inflammation, and promoting healing.
Studies further indicate that Zinc Pyrithione significantly reduces the production of pro-inflammatory cytokines interleukin-1 and tumor necrosis factor-alpha. This action boosts the body’s natural defenses against yeast and reduces the severity of skin irritation.
Cytokine production is a complex process involving a balance between pro-inflammatory and anti-inflammatory cytokines. Zinc Pyrithione supports a healthy balance between inflammation and immune function, helping to manage skin sensitivity and irritation.
Zinc Pyrithione also has direct anti-inflammatory effects on the skin by reducing the production of certain enzymes that contribute to inflammation.

Anti-fungal

Zinc Pyrithione has broad-spectrum antimicrobial activity, inhibiting and reducing the burden of Malassezia yeast on the skin. It targets gram-positive and gram-negative bacteria, as well as other fungi that cause common fungal infections like ringworm, athlete's foot, and jock itch.
Zinc Pyrithione disrupts iron distribution across the yeast cell wall, effectively starving the yeast by interfering with essential respiratory functions.
Zinc Pyrithione disrupts the yeast’s cell membrane, preventing it from proliferating and reproducing. It binds to the yeast’s cell membrane, causing structural damage that ultimately leads to cell death.
Zinc Pyrithione also interferes with the metabolic processes of the yeast, disrupting the uptake of essential nutrients and altering the skin’s pH balance, making it more challenging for the yeast to survive and grow.
Zinc Pyrithione has a unique slow-release ability, persisting in the top layer of skin even after rinsing. This property imparts long-lasting control and sustained release of anti-yeast coverage, effectively suppressing Malassezia yeast overgrowth.
Yeast, fungi, and bacteria do not develop resistance to Zinc Pyrithione, allowing consistent application to provide continuous antimicrobial activity.

zinc pyrithione

effective treatment for skin conditions

atopic dermatitis and eczema

action

ZnPT formulated in body treatment is adjunctive to corticosteroid use for managing atopic dermatitis and eczema.
ZnPT alters skin levels of Malassezia yeast or Staphylococcus aureus bacteria, which is important in aggravating atopic dermatitis.
Malessezia yeast and its metabolites cause barrier aggravation in atopic dermatitis and eczema.
Approximately half of the differentially expressed stratum corneum proteins from dandruff and atopic dermatitis are the same, suggesting a common etiology.

evidence

A randomized controlled trial in children showed the benefits of ZnPT with lipids on skin microbiome diversity and atopic dermatitis score (SCORAD) when used in conjunction with 0.1% w/v hydrocortisone butyrate cream.

skin infection

action	ZnPT in antiseptic products has a significant clinical impact, such as reducing surgical site infections through extended anti-microbial persistence.
evidence	In an expanded flora test on the forearm, ZnPT exhibits gradual activity against a broad spectrum of gram-negative and gram-positive bacteria and RNA and DNA viruses for up to three days. Concentrations up to 0.25% ZnPT with alcohol were superior to other combination agents (e.g., iodine, chlorhexidine gluconate, and triclosan) for the persistence of antimicrobial effects.

uvb induced hyperplasia

action	ZnPT treatment prevents UVB-induced photoaging and skin cancer development, potentially as an additive to sunscreens. Further work is needed to demonstrate human efficacy and establish therapeutic doses.
evidence	1% ZnPT scalp treatment prevented skin thickening in study subjects exposed to UVB radiation and normalized levels of hypoxia-inducible factor-1α, influencing the cell cycle.

	atopic dermatitis and eczema	skin infection	uvb induced hyperplasia
action	ZnPT formulated in body treatment is adjunctive to corticosteroid use for managing atopic dermatitis and eczema. ZnPT alters skin levels of Malassezia yeast or Staphylococcus aureus bacteria, which is important in aggravating atopic dermatitis. Malessezia yeast and its metabolites cause barrier aggravation in atopic dermatitis and eczema. Approximately half of the differentially expressed stratum corneum proteins from dandruff and atopic dermatitis are the same, suggesting a common etiology.	ZnPT in antiseptic products has a significant clinical impact, such as reducing surgical site infections through extended anti-microbial persistence.	ZnPT treatment prevents UVB-induced photoaging and skin cancer development, potentially as an additive to sunscreens. Further work is needed to demonstrate human efficacy and establish therapeutic doses.
evidence	A randomized controlled trial in children showed the benefits of ZnPT with lipids on skin microbiome diversity and atopic dermatitis score (SCORAD) when used in conjunction with 0.1% w/v hydrocortisone butyrate cream.	In an expanded flora test on the forearm, ZnPT exhibits gradual activity against a broad spectrum of gram-negative and gram-positive bacteria and RNA and DNA viruses for up to three days. Concentrations up to 0.25% ZnPT with alcohol were superior to other combination agents (e.g., iodine, chlorhexidine gluconate, and triclosan) for the persistence of antimicrobial effects.	1% ZnPT scalp treatment prevented skin thickening in study subjects exposed to UVB radiation and normalized levels of hypoxia-inducible factor-1α, influencing the cell cycle.

Targets Malassezia Yeast: Zinc Pyrithione is particularly effective against Malassezia yeast, a fungus commonly found on the skin and scalp. This yeast can proliferate excessively, leading to dandruff and seborrheic dermatitis.

Disrupts Fungal Cell Membranes: Zinc Pyrithione works by disrupting the fungus's cell membranes, inhibiting its growth and survival. This action reduces the fungal population on the skin, alleviating symptoms associated with overgrowth.

Broad-Spectrum Activity: Zinc Pyrithione also possesses antibacterial properties that are effective against various bacteria that can contribute to skin irritation and infection. Reducing bacterial load helps prevent secondary infections and promotes skin healing.

Inhibits Bacterial Enzyme Systems: It interferes with enzyme systems within bacterial cells, leading to their death. This mechanism helps maintain skin flora balance and prevents conditions like acne and folliculitis.

mode of action

zinc pca

rosacea and acne treatment

anti-bacterial

Zinc PCA hinders microbial growth. Its antiseptic properties limit the proliferation of acne-causing bacteria in the skin.

sebum (oil) regulator

It inhibits the activity of the 5 alpha-reductase enzymes to control excessive sebum production.

anti-inflammatory

Inhibits mast cell degranulation and thereby reduces histamine secretion, an important mediator of inflammatory response.

Testimonials

Great stuff!

My absolute favorite face wash 😊

Pore Control Cleanser

Wonder product. I will never use anything else

Did not think this would change my life! (it did)

Absolutely glowing in winter! I'm never using any other cleanser in my life. Already convinced my mom and sister to try it out!

5 stars

Very good service and fast delivery. The product itself is a 10 out of 10. My acne has reduced so much since I started using the cleanser a year ago. Love it !

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Medi-Zinc Cleanser

zinc pyrithione

mode of action

Customer Reviews