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Chemical Peel Spray: Trial
Chemical Peel Spray: Trial
Chemical Peel Spray: Trial Chemical Peel Spray: Trial Chemical Peel Spray: Trial Chemical Peel Spray: Trial
DermExcel™

Chemical Peel Spray: Trial

4.9 / 5.0 from 464 reviews
Exfoliating

Exfoliating

Smooth Skin

Smooth Skin

Ingrown hair

Ingrown hair

Anti-Acne

Anti-Acne

Anti-Aging

Anti-Aging

Chemical Peel Spray, fortified with a blend of 10% Glycolic acid and 3% Salicylic acid, is a potent skincare solution designed to combat the visible signs of aging and address body acne concerns, including back and buttocks acne. Crafted with medical-grade ingredients, this innovative formula offers a multifaceted approach to skin rejuvenation.

Salicylic acid facilitates deep penetration into the pores, effectively targeting and eliminating pimples, blackheads, Keratosis Pilaris, and unsightly ingrown hair bumps. By exfoliating the skin's surface, this powerful ingredient helps unclog congested pores, promoting a clearer complexion.

Chemical Peel Spray has a rapid drying time. Within seconds of application, the liquid thoroughly dries on the skin without leaving any residue. This unique attribute allows for hassle-free use, enabling you to conveniently apply the product and proceed with your daily routine without concerns of fabric staining.

Chemical Peel Spray embodies the convergence of scientific expertise and dermatological innovation. Empower yourself with this exceptional skincare solution, engineered to enhance your skin's appearance and restore its natural radiance.

Glycolic acid
Glycolic acid

Glycolic acid is highly acclaimed for its remarkable exfoliating and rejuvenating properties. Its small molecular size enables deep skin penetration, fostering efficient exfoliation at the cellular level.

Glycolic acid’s water solubility allows it to penetrate the upper layers of the skin easily. Its primary mechanism of action involves weakening the bonds between dead skin cells, promoting their shedding, and revealing the newer, healthier skin beneath. This process of accelerated cell turnover is instrumental in addressing a range of skin concerns, from aging signs like fine lines and wrinkles to texture irregularities and hyperpigmentation.

Glycolic acid's efficacy extends beyond mere exfoliation. It's also recognized for stimulating collagen production, a crucial protein in maintaining skin's elasticity and firmness. This aspect contributes to its anti-aging benefits. Furthermore, its hydrating properties add to its appeal, as they help increase the skin's capacity to retain moisture, leading to a more supple and vibrant complexion.

Clinical studies have consistently supported glycolic acid's role in improving skin appearance. Research indicates significant improvements in skin texture and pigmentation and the visible reduction of wrinkles and fine lines with glycolic acid.

Physiological Effects
  • Exfoliation: Glycolic acid is a powerful exfoliant. It dissolves the bonds between dead skin cells on the skin’s surface, facilitating their removal and revealing newer, healthier skin underneath.
  • Increased Collagen Production: It stimulates collagen production, which is essential for skin elasticity and firmness. This action helps reduce the appearance of fine lines and wrinkles.
  • Enhanced Skin Hydration: Glycolic acid improves the skin's ability to retain moisture, enhancing hydration and a more plump, vibrant skin appearance.
  • Skin Brightening: Removing dead skin cells can brighten the complexion and reduce the appearance of dark spots and hyperpigmentation.
  • Improved Skin Texture: Regular use of glycolic acid can lead to smoother, more even textured skin, making it beneficial for conditions like keratosis pilaris.
  • Acne Treatment: Its exfoliating properties help in unclogging pores, thereby reducing the occurrence of acne breakouts.

Role in Managing Dermatological Conditions
  • Aging Skin: Glycolic acid is widely used in anti-aging products to reduce signs of aging, such as fine lines, wrinkles, and age spots.
  • Acne-Prone Skin: It helps manage acne by exfoliating the skin and removing blockage from pores.
  • Hyperpigmentation: It effectively treats hyperpigmentation by accelerating the removal of hyperpigmented skin cells.
  • Textural Irregularities: Glycolic acid can improve skin texture and is beneficial for treating keratosis pilaris and other conditions of rough skin.
  • Sun-Damaged Skin: It helps rejuvenate sun-damaged skin by accelerating cell turnover and collagen synthesis.

References
  • Bernstein, E. F. (2001). Glycolic acid treatment increases type I collagen mRNA and hyaluronic acid content of human skin. Dermatologic Surgery.
  • Kornhauser, A., Coelho, S. G., & Hearing, V. J. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, Cosmetic and Investigational Dermatology.
  • Sharad, J. (2013). Glycolic acid peel therapy – a current review. Clinical, Cosmetic and Investigational Dermatology.
  • Smith, W. P. (1996). Epidermal and dermal effects of topical lactic acid. Journal of the American Academy of Dermatology, 35(3), 388-391.
Salicylic acid
Salicylic acid

Salicylic acid, a renowned beta hydroxy acid (BHA), is a cornerstone in dermatology and skincare due to its exceptional keratolytic and comedolytic properties. Its unique ability to penetrate oil-laden hair follicle pores makes it particularly effective in treating acne-prone and oily skin types.

Salicylic acid dissolves skin debris (sebum and dead skin cells) that clogs pores and causes acne. It's a mild antibacterial and powerful anti-inflammatory agent that helps reduce the redness and swelling associated with breakouts.

What sets salicylic acid apart in dermatological treatments is its ability to exfoliate the skin, not just on the surface but within the pores themselves. This is due to its oil-soluble nature, which allows it to penetrate deep into the pores and dissolve the keratin plugs that lead to blackheads and whiteheads.

Furthermore, salicylic acid also has the capacity to adjust the pH of the skin, creating an environment less favorable for the growth of acne-causing bacteria. Salicylic acid's efficacy in treating various skin conditions, particularly acne, has been extensively documented in the scientific literature. Studies have consistently shown its ability to reduce acne lesions in terms of count and severity. Additionally, salicylic acid is highly recommended for its effectiveness in treating other skin conditions, such as psoriasis and dandruff, due to its ability to soften and remove scales and flakes from the skin.

Physiological Effects
  • Keratolytic Action: Salicylic acid is known for its ability to exfoliate the skin by dissolving the intercellular 'glue' that holds skin cells together, helping to remove dead skin cells and unclog pores.
  • Comedolytic Effect: It is particularly effective in reducing comedones (blackheads and whiteheads) by unclogging pores and preventing the formation of new comedones.
  • Anti-inflammatory Properties: Salicylic acid reduces inflammation, which is beneficial in treating acne and other inflammatory skin conditions.
  • Sebum Regulation: It helps to regulate oil production, making it a valuable ingredient for managing oily and acne-prone skin.
  • Penetration Enhancement: Due to its lipophilic nature, it can penetrate sebum-filled follicles, effectively treating acne located deep within the pores.

Role in Managing Dermatological Conditions
  • Acne Vulgaris: Salicylic acid is a cornerstone in acne treatment, effectively preventing and treating existing acne lesions.
  • Psoriasis: Its keratolytic properties make it helpful in softening and removing scales associated with psoriasis.
  • Warts: Salicylic acid is commonly used to treat warts because it can exfoliate and remove thick skin.
  • Seborrheic Dermatitis: It helps manage seborrheic dermatitis by reducing scaling and redness.
  • Keratosis Pilaris: Salicylic acid can aid in smoothing the rough bumps associated with peratosis Pilaris.

References
  • Zaenglein, A. L., Pathy, A. L., Schlosser, B. J., Alikhan, A., Baldwin, H. E., Berson, D. S., & Thiboutot, D. M. (2016). Guidelines of care for the management of acne vulgaris. Journal of the American Academy of Dermatology, 74(5), 945-973.e33.
  • Kornhauser, A., Coelho, S. G., & Hearing, V. J. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, cosmetic and investigational dermatology, 3, 135.
  • Zander, E., & Weisman, S. (1992). Treatment of acne vulgaris with salicylic acid pads. Clinical Therapeutics.
  • Gupta, A. K., & Nicol, K. (2004). The use of sulfur in dermatology. Journal of Drugs in Dermatology.
Chemical Peel Spray: Trial Chemical Peel Spray: Trial Chemical Peel Spray: Trial Chemical Peel Spray: Trial
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  • Acne Vulgaris: Salicylic acid penetrates the pores to eliminate excess sebum and dead skin cells, effectively treating and preventing acne.
  • Body Acne: Treat acne on the back, buttocks, and other body parts.
  • Keratosis Pilaris: The exfoliating action reduces the small, rough bumps caused by this condition.
  • Blackheads and Whiteheads: By dissolving excess oil and dead skin cells, the spray help clear these common forms of acne.
  • Hyperpigmentation: Glycolic acid accelerates cell turnover, which improves uneven skin tone and reduces dark spots.
  • Signs of Aging: The increased cell turnover and collagen production stimulated by Glycolic acid help to reduce fine lines, wrinkles, and other signs of aging.
  • Ingrown Hairs: Salicylic acid reduce inflammation and smooth away bumps caused by ingrown hairs.
  • Rough and Uneven Skin Texture: Regular use leads to smoother, more even skin due to the exfoliating properties of the acids.
  • Folliculitis: Help manage the inflammation of hair follicles and inhibit the growth of bacteria that contribute to folliculitis.

Active ingredients
  • Glycolic acid
    • Glycolic acid

    Salicylic acid, a renowned beta hydroxy acid (BHA), is a cornerstone in dermatology and skincare due to its exceptional keratolytic and comedolytic properties. Its unique ability to penetrate oil-laden hair follicle pores makes it particularly effective in treating acne-prone and oily skin types.

    Salicylic acid dissolves skin debris (sebum and dead skin cells) that clogs pores and causes acne. It's a mild antibacterial and powerful anti-inflammatory agent that helps reduce the redness and swelling associated with breakouts.

    What sets salicylic acid apart in dermatological treatments is its ability to exfoliate the skin, not just on the surface but within the pores themselves. This is due to its oil-soluble nature, which allows it to penetrate deep into the pores and dissolve the keratin plugs that lead to blackheads and whiteheads.

    Furthermore, salicylic acid also has the capacity to adjust the pH of the skin, creating an environment less favorable for the growth of acne-causing bacteria. Salicylic acid's efficacy in treating various skin conditions, particularly acne, has been extensively documented in the scientific literature. Studies have consistently shown its ability to reduce acne lesions in terms of count and severity. Additionally, salicylic acid is highly recommended for its effectiveness in treating other skin conditions, such as psoriasis and dandruff, due to its ability to soften and remove scales and flakes from the skin.
    • Keratolytic Action: Salicylic acid is known for its ability to exfoliate the skin by dissolving the intercellular 'glue' that holds skin cells together, helping to remove dead skin cells and unclog pores.
    • Comedolytic Effect: It is particularly effective in reducing comedones (blackheads and whiteheads) by unclogging pores and preventing the formation of new comedones.
    • Anti-inflammatory Properties: Salicylic acid reduces inflammation, which is beneficial in treating acne and other inflammatory skin conditions.
    • Sebum Regulation: It helps to regulate oil production, making it a valuable ingredient for managing oily and acne-prone skin.
    • Penetration Enhancement: Due to its lipophilic nature, it can penetrate sebum-filled follicles, effectively treating acne located deep within the pores.
    • Acne Vulgaris: Salicylic acid is a cornerstone in acne treatment, effectively preventing and treating existing acne lesions.
    • Psoriasis: Its keratolytic properties make it helpful in softening and removing scales associated with psoriasis.
    • Warts: Salicylic acid is commonly used to treat warts because it can exfoliate and remove thick skin.
    • Seborrheic Dermatitis: It helps manage seborrheic dermatitis by reducing scaling and redness.
    • Keratosis Pilaris: Salicylic acid can aid in smoothing the rough bumps associated with peratosis Pilaris.
    • Zaenglein, A. L., Pathy, A. L., Schlosser, B. J., Alikhan, A., Baldwin, H. E., Berson, D. S., & Thiboutot, D. M. (2016). Guidelines of care for the management of acne vulgaris. Journal of the American Academy of Dermatology, 74(5), 945-973.e33.
    • Kornhauser, A., Coelho, S. G., & Hearing, V. J. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, cosmetic and investigational dermatology, 3, 135.
    • Zander, E., & Weisman, S. (1992). Treatment of acne vulgaris with salicylic acid pads. Clinical Therapeutics.
    • Gupta, A. K., & Nicol, K. (2004). The use of sulfur in dermatology. Journal of Drugs in Dermatology.
  • Salicylic acid
    • Salicylic acid

    Salicylic acid, a renowned beta hydroxy acid (BHA), is a cornerstone in dermatology and skincare due to its exceptional keratolytic and comedolytic properties. Its unique ability to penetrate oil-laden hair follicle pores makes it particularly effective in treating acne-prone and oily skin types.

    Salicylic acid dissolves skin debris (sebum and dead skin cells) that clogs pores and causes acne. It's a mild antibacterial and powerful anti-inflammatory agent that helps reduce the redness and swelling associated with breakouts.

    What sets salicylic acid apart in dermatological treatments is its ability to exfoliate the skin, not just on the surface but within the pores themselves. This is due to its oil-soluble nature, which allows it to penetrate deep into the pores and dissolve the keratin plugs that lead to blackheads and whiteheads.

    Furthermore, salicylic acid also has the capacity to adjust the pH of the skin, creating an environment less favorable for the growth of acne-causing bacteria. Salicylic acid's efficacy in treating various skin conditions, particularly acne, has been extensively documented in the scientific literature. Studies have consistently shown its ability to reduce acne lesions in terms of count and severity. Additionally, salicylic acid is highly recommended for its effectiveness in treating other skin conditions, such as psoriasis and dandruff, due to its ability to soften and remove scales and flakes from the skin.
    • Keratolytic Action: Salicylic acid is known for its ability to exfoliate the skin by dissolving the intercellular 'glue' that holds skin cells together, helping to remove dead skin cells and unclog pores.
    • Comedolytic Effect: It is particularly effective in reducing comedones (blackheads and whiteheads) by unclogging pores and preventing the formation of new comedones.
    • Anti-inflammatory Properties: Salicylic acid reduces inflammation, which is beneficial in treating acne and other inflammatory skin conditions.
    • Sebum Regulation: It helps to regulate oil production, making it a valuable ingredient for managing oily and acne-prone skin.
    • Penetration Enhancement: Due to its lipophilic nature, it can penetrate sebum-filled follicles, effectively treating acne located deep within the pores.
    • Acne Vulgaris: Salicylic acid is a cornerstone in acne treatment, effectively preventing and treating existing acne lesions.
    • Psoriasis: Its keratolytic properties make it helpful in softening and removing scales associated with psoriasis.
    • Warts: Salicylic acid is commonly used to treat warts because it can exfoliate and remove thick skin.
    • Seborrheic Dermatitis: It helps manage seborrheic dermatitis by reducing scaling and redness.
    • Keratosis Pilaris: Salicylic acid can aid in smoothing the rough bumps associated with peratosis Pilaris.
    • Zaenglein, A. L., Pathy, A. L., Schlosser, B. J., Alikhan, A., Baldwin, H. E., Berson, D. S., & Thiboutot, D. M. (2016). Guidelines of care for the management of acne vulgaris. Journal of the American Academy of Dermatology, 74(5), 945-973.e33.
    • Kornhauser, A., Coelho, S. G., & Hearing, V. J. (2010). Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clinical, cosmetic and investigational dermatology, 3, 135.
    • Zander, E., & Weisman, S. (1992). Treatment of acne vulgaris with salicylic acid pads. Clinical Therapeutics.
    • Gupta, A. K., & Nicol, K. (2004). The use of sulfur in dermatology. Journal of Drugs in Dermatology.

Full ingredient list

    Aqua, Propylene glycol, Glycolic acid, Salicylic acid, Glycerin, Polyacrylamide & C13-14 Isoparaffin & Laureth-7, Triethanolamine, Hydroxyethylcellulose, Potassium hydroxide

Evening
  • Application time: Evening.
  • Frequency: 2-3 times per week as tolerated by your skin, or follow your Dermal Diagnosis treatment plan instructions. Once an affected area becomes clear, occasional use will maintain remission. 

1. Cleanse
  • Start with clean and dry skin.
  • Use your DermExcel cleanser to remove dirt and excess oil from your skin.

2: Apply
  • Dispense a small amount of product onto your fingertips.
  • Apply evenly over your face or on body areas of concern.
  • Avoid sensitive areas, e.g., the eyes and lips.

Important note
  • Start by applying this exfoliator one evening per week. After one week, increase usage to two evenings a week.
  • Observe how your skin responds and adjust usage accordingly.
  • You may use this treatment every second night if you don't have sensitive skin.
  • Don't apply any other product to the area treated with your exfoliating treatment. The other product may alter the pH of the active ingredients, lowering the product's potency. 
  • This exfoliating treatment promotes skin peeling by effectively removing dead skin cells. Peeling is a normal reaction and not a sign of skin dryness. You should notice decreased peeling as the product works to exfoliate dead skin.
  • You may notice a slight stickiness on your skin after applying your exfoliating product. This sensation is typical due to the hydroxyethylcellulose, a thickening agent that helps the treatment adhere to the skin. This allows the active ingredients to work effectively throughout the night by promoting exfoliation and cell turnover. Embrace this as a sign that the active ingredients are set to rejuvenate your skin while you sleep without the inconvenience of daytime residue.
  • Always use SPF 30 or greater during the day.

chemical peel spray

mode of action

salicylic acid vs. glycolic acid

Salicylic acid

  • Lipophilic (oil-soluble), allowing it to penetrate the skin's pores.
  • Dissolves the intercellular 'glue' that holds skin cells together and penetrates deep into the pores to dissolve excess sebum and dead skin cells, reducing blockages.
  • Effective in treating acne and blackheads by unclogging pores.
  • It has anti-inflammatory and antimicrobial action that reduces redness and inflammation associated with acne and rosacea.
  • Improves the skin texture by exfoliation.

glycolic acid

  • Hydrophilic (water-soluble) effectively exfoliates the skin's surface layers.
  • Primarily acts on the skin's surface, dissolving the bonds that hold dead skin cells on the surface, which helps promote exfoliation and cell regeneration.
  • Exfoliate the skin, improving texture and revealing brighter, more youthful skin.
  • Stimulates collagen production, reducing the appearance of lines and wrinkles.
  • Fade hyperpigmentation and even out skin tone.

the stages of acne

Step 1

Step 1

Regulate sebum (oil) production and secretion

  • The excretion of lipids by the sebaceous glands is controlled hormonally.
  • The sebaceous glands are located all over the body but are the largest and most numerous in the face, back, chest, and shoulders.
  • These glands become more active during puberty because of increased androgens, particularly testosterone, which spurs sebum production.
  • This imbalance between sebum production and secretion capacity leads to a blockage of sebum in the hair follicle, followed by inflammation.
  • Hormones continue to affect sebaceous gland activity into adulthood.

Step 2

Step 2

Prevent and remove content build-up in pores

  • The first stage of acne is called comedogenesis (formation of comedones).
  • The exfoliated dead skin cells stick together inside the hair follicle, resulting in a clogged pore or comedone.
  • This is caused by several factors, including increased amounts of sebum, inflammation of the sides of the hair follicle preventing the release of the exfoliated keratinocytes, and increased cohesion of keratinocytes.
  • Salicylic acid decongests pores by dissolving and extracting dirt, oil, and cellular debris (dead skin cells) in the pores and follicles.

Step 3

Step 3

Prevent Bacterial Infiltration and infection

  • The keratinocyte plug and sebum provide excellent food sources for bacteria.
  • The bacteria invade the comedone and release inflammatory factors that lead to the next stage of acne.
  • Salicylic acid inhibits the production of various aspects necessary for bacterial reproduction, such as fibrinogen, fibronectin, and alpha-hemolysis.

Step 4

Step 4

Down-regulate and prevent inflammation

  • Inflammation continues with increased redness and pus.
  • This is clinically detectable as a papule or pustule.
  • Continued inflammation may lead to so much inflammation that the hair follicle ruptures and the bacteria and debris are released into the dermis.
  • Salicylic acid suppresses pro-inflammatory cytokine expression.

salicylic acid targets all phases of the acne process